Aebersold, R., Auffray, C., Baney, E., Barillot, E., Brazma, A., Brett, C., Brunak, S., Butte, A., Califano, A., Celis, J., Cufer, T., Ferrell, J., Galas, D., Gallahan, D., Gatenby, R., Goldbeter, A., Hace, N., Henney, A., Hood, L., Iyengar, R., Jackson, V., Kallioniemi, O., Klingmuller, U., Kolar, P., Kolch, W., Kyriakopoulou, C., Laplace, F., Lehrach, H., Marcus, F., Matrisian, L., Nolan, G., Pelkmans, L., Potti, A., Sander, C., Seljak, M., Singer, D., Sorger, P., Stunnenberg, H., Superti-Furga, G., Uhlen, M., Vidal, M., Weinstein, J., Wigle, D., Williams, M., Wolkenhauer, O., Zhivotovsky, B., Zinovyev, A., and Zupan, B. Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008).
Mol.Oncol. 2009: 3(1), 9-17
Andrejevs, G., Celis, J. E., Guidi, G., Peterle, A., Sullivan, R., and Wilson, R. 'Tackling cancer in the EU: the role of innovation'.
Mol.Oncol. 2009: 3(1), 18-23
Cardoso, C. M., Groth-Pedersen, L., Høyer-Hansen, M., Kirkegaard, T., Corcelle, E., Andersen, J. S., Jäättelä, M., and Nylandsted, J. Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells.
PLoS.ONE. 2009: 4(2), e4424
Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, S., Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, J., and Weitzman, M. D. Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.
EMBO J. 2009: 28(6), 652-662
Celis, J. E. Thematic Issues.
Mol.Oncol. 2009
Celis, J. E., Cabezon, T., Moreira, J. M., Gromov, P., Gromova, I., Timmermans-Wielenga, V., Iwase, T., Akiyama, F., Honma, N., and Rank, F. Molecular characterization of apocrine carcinoma of the breast: Validation of an apocrine protein signature in a well-defined cohort.
Mol.Oncol. 2009
Danielsen, J. M., Larsen, D. H., Schou, K. B., Freire, R., Falck, J., Bartek, J., and Lukas, J. HCLK2 is required for activity of the DNA damage response kinase ATR.
J.Biol.Chem. 2009: 284(7), 4140-4147
Doil, C., Mailand, N., Bekker-Jensen, S., Menard, P., Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, J., and Lukas, C. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
Cell 2009: 136(3), 435-446
Faustrup, H., Bekker-Jensen, S., Bartek, J., Lukas, J., and Mailand, N. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin.
J.Cell Biol. 2009: 184(1), 13-19
Frogne, T., Laenkholm, A. V., Lyng, M. B., Henriksen, K. L., and Lykkesfeldt, A. E. Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors.
Breast Cancer Res. 2009: 11(1), R11
Frogne, T., Benjaminsen, R. V., Sonne-Hansen, K., Sorensen, B. S., Nexo, E., Laenkholm, A. V., Rasmussen, L. M., Riese, D. J., de, Cremoux P., Stenvang, J., and Lykkesfeldt, A. E. Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant.
Breast Cancer Res.Treat. 2009: 114(2), 263-275
Henriksen, K. L., Rasmussen, B. B., Lykkesfeldt, A. E., Moller, S., Ejlertsen, B., and Mouridsen, H. T. An ER activity profile including ER, PR, Bcl-2 and IGF-IR may have potential as selection criterion for letrozole or tamoxifen treatment of patients with advanced breast cancer.
Acta Oncol. 2009: 48(4), 522-531
Herrero-Martin, G., Høyer-Hansen, M., Garcia-Garcia, C., Fumarola, C., Farkas, T., Lopez-Rivas, A., and Jäättelä, M. TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells.
EMBO J. 2009: 28(6), 677-685
Hofmeister-Mueller, V., Vetter-Kauczok, C. S., Ullrich, R., Meder, K., Lukanidin, E., Broecker, E. B., Straten, P., Andersen, M. H., Schrama, D., and Becker, J. C. Immunogenicity of HLA-A1-restricted peptides derived from S100A4 (metastasin 1) in melanoma patients.
Cancer Immunol.Immunother. 2009: 58(8), 1265-1273
Jensen, L. B., Bartlett, J. M., Witton, C. J., Kirkegaard, T., Brown, S., Muller, S., Campbell, F., Cooke, T. G., and Nielsen, K. V. Frequent amplifications and deletions of G1/S-phase transition genes, CCND1 and MYC in early breast cancers: A potential role in G1/S escape.
Cancer Biomark. 2009: 5(1), 41-49
Liontos, M., Niforou, K., Velimezi, G., Vougas, K., Evangelou, K., Apostolopoulou, K., Vrtel, R., Damalas, A., Kontovazenitis, P., Kotsinas, A., Zoumpourlis, V., Tsangaris, G. T., Kittas, C., Ginsberg, D., Halazonetis, T. D., Bartek, J., and Gorgoulis, V. G. Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas.
Am.J.Pathol. 2009: 175(1), 376-391
Lukas, J. and Bartek, J. DNA repair: New tales of an old tail.
Nature 2009: 458(7238), 581-583
Tibelius, A., Marhold, J., Zentgraf, H., Heilig, C. E., Neitzel, H., Ducommun, B., Rauch, A., Ho, A. D., Bartek, J., and Kramer, A. Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1.
J.Cell Biol. 2009: 185(7), 1149-1157