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Hjernetumorbiologi - videnskabelige artikler


Rasmussen RD, et al., Hamerlik P. BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity. Nature Communications e-pub ahead of print.

Staberg M al., Hamerlik P. Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine. (2016) Cellular Oncology e-pub ahead of print.

Staberg M et al., P. Hamerlik and Hans Skovgaard Poulsen. Combined EGFR- and Notch inhibition display additive inhibitory effect on Glioblastoma cell viability and Glioblastoma-induced endothelial cell sprouting in vitro. (2016) Cancer Cell International (accepted).

Rasmussen RD, et al., Hamerlik P. Synergistic inhibition of GBM cell survival by co-targeting HDAC and PARP. (2015) Molecular Oncology. 10:751-63.

Schonberg DL, et al., Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN. Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. (2015) Cancer Cell. 28:441-55.

Rivera M., Wu Q., Hamerlik P., Hjelmeland A.B., Bao S., Rich J.N. (2015) Acquisition of meiotic DNA repair regulators maintain genome stability in glioblastoma. Cell Death Dis. 6:e1732.

Venere, M.#, Hamerlik, P.# et al. (2013) Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma initiating cells. Cell Death and Differentiation 21: 258-69. #equal contribution-shared first author

Kim, Y., Wu, Q., Hamerlik P., Hitomi, M., Sloan, A.E., Barnett, G.H., Weil, R.J., Leahy, P., Hjelmeland, A.B., and Rich, J.N. (2013) Aptamer Identification of Brain Tumor–Initiating Cells. Cancer Research 73: 4923-36.

Hamerlik P, et al. (2012) Autocrine VEGFR2 signaling contributes to glioma stem-like cell viability and tumor growth. Journal of Experimental Medicine 209: 507-20.


Karottki JL, Azam A, Hamerlik P. (2015) The heterogeneity and therapeutic resistance of glioblastoma. Medical Research Archives 3:1-10.

Hamerlik P., Rich JN., Lathia J. (2013) News & views basic science: glioblastoma stem cells. EANO 2: 2224-3453.


Hamerlik, P. Glioma Cell Biology: Stem Cells in Glioblastoma. Invited book Chapter. 2014, Springer Verlag.