Senior Scientist: Daniela De Zio

As previous member of the European Consortium “MEL-PLEX - exploiting MELanoma disease comPLEXity” (ITN-Horizon2020) aimed at investigating the network-level and regulation of disease-relevant signaling in melanoma, Daniela De Zio's principal interest deals with melanoma research.

Recently, she has started a new line of research in the CSS group aimed at finding novel prognostic markers and therapeutic targets for melanoma by means of genetically engineered mouse models.

Daniela De Zio has strong expertise in cell/molecular biology and mouse genetics/manipulation. These skills have been crucial for the set-up of a melanoma mouse model carrying the human-relevant driver mutations of BRAF and PTEN genes, which are found in more than 50% of melanoma patients. This is a highly predictive preclinical model resembling the human disease, which has been proven to be instrumental for studying novel tumor suppressors in melanomagenesis and melanoma progression, and for testing new therapeutic drugs.

Recently, Daniela De Zio has obtained grants from different funding agencies allowing her to establish the Melanoma Research Team in CSS. Among those, the very prestigious Young Investigator Award from the American association Melanoma Research Alliance is worth to mention. She is an associated professor at the Department of Drug Design and Pharmacology, University of Copenhagen.


 

Senior scientist Daniela De Zio 

ORCID: 0000-0002-9454-402X


Key Funding

LEO Foundation

Danish Cancer Society Scientific Committee

Melanoma Research Alliance - Young Investigator Award

NEYE Foundation