Sitemap
  Forside  
  Hjælp og viden  
  Forebyg kræft  
  Støt os  
  Forskning  
  Til fagfolk  
  Nyheder  
  Om os  
cancer.dk
  Research  
  Structure  
  Funding  
  Education and recruitment  
  Open positions  
  Location  
  Contact us  
  Links  
  Publications  
  Groups
Adresse Genotoxic
Center for Genotoxic
Stress Research
Danish Cancer Society

Strandboulevarden 49
DK-2100 Copenhagen
Denmark

Phone: +45 3525 7799
genotoxic@cancer.dk

 

Lab members

(Asterix indicates people directly funded by the Danish National Research Foundation)

 

 

description

Name

Jiri Bartek

Position

Department Head, M.D., PhD

E-mail & phone

jb@cancer.dk

Phone no.:
+45 35 25 73 57

Nationality

Czech

Research Interest



Cellular and molecular basis of cell cycle checkpoints.

Functional links between DNA damage signalling and DNA repair.

Defect in DNA damage responses and their contribution to human cancer.



description

Name

Jiri Lukas

Position

Director of the Centre, Vet. M.D., PhD

E-mail & phone

jil@cancer.dk

Phone no.:
+45 35 25 73 10

Nationality

Czech

Research Interest



Regulation of the mammalian cell division cycle.

Biological responses to genotoxic stress.

Non-invasive imaging of molecular interactions in live cells.

    description

    Name

    Guarn Whitaker-Nissen*

    Position

    Administrative Coordinator of the Genotoxic Stress Research Centre

    E-mail & phone

    gwn@cancer.dk

    Phone no.:
    +45 35 25 77 99

    Nationality

    American

     
    Til top
     

    Name

    Doris Vejby-Sørensen

    Position

    Research Secretary

    E-mail & phone

    vejby@cancer.dk

    Phone no.:
    +45 35 25 73 94

    Nationality

    Danish

    description

    Name

    Claudia Lukas

    Position

    Senior Scientist

    E-mail & phone

    clukas@cancer.dk

    Phone no.:
    +45 35 25 73 10

    Nationality

    German

    Research Interest



    Live cell imaging of DNA damage checkpoint responses.

    description

    Name

    Jirina Bartkova

    Position

    Senior Scientist, M.D., PhD

    E-mail & phone

    jba@cancer.dk
    Phone no.:
    +45 35 25 72 95

    Nationality

    Czech

    Research Interest



    The role of DNA damage response pathways in human cancer and aging.

    Immuneohistochemaical analyses of proteins involved in cell cycle checkpoints and DNA repair.

    Focus on tumours of the breast, urinary bladder, colan and testis.

    Name

    Sugiko Watanabe

    Position

    Senior Scientist, M.D, PhD

    E-mail & phone

    sugwat@cancer.dk
    Phone no.:
    +45 35 25 77 89

    Nationality

    Japanese

    Research Interest



    Epigenetic responses to genotoxic stress in stem cells, differentiated cells and tumor cells. Development of cancer therapy based on molecular biology.

    Name

    Velibor Savic

    Position

    Postdoc, PhD

    E-mail & phone

    savic@cancer.dk

    Phone no.:
    +45 35 25 77 89

    Nationality

    Croatian

    Research Interest



    Elucidating the spatial distribution of DNA damage response machinery in response to DNA lesions in order to both better explain the mechanisms of error-free repair and understand events that lead to miss-repair and translocations.

    Name

    Christoffel Dinant

    Position

    Postdoc, PhD

    E-mail & phone

    cdi@cancer.dk

    Phone no.:
    +45 35 25 77 65

    Nationality

    Dutch

    Research Interest



    Usage of live cell confocal microscopy techniques to study the behavior of proteins involved in the DNA damage response and usage of a high-throughput siRNA screen to identify novel players in the DNA damage response.

    Name

    Masayuki Yamada

    Position

    Postdoc, PhD

    E-mail & phone

    mya@cancer.dk

    Phone no.:
    +45 35 25 73 34

    Nationality

    Japanese

    Research Interest



    To clarify the molecular mechanism of DNA damage response caused by aberrant DNA reåplication and apply it to cancer treatment.

    Name

    Petra Hamerlik

    Position

    Postdoc, PhD

    E-mail & phone

    pkn@cancer.dk

    Phone no.:
    +45 35 25 77 65

    Nationality

    Slovakian

    Research Interest



    Separation of CD133-positive cancer stem-like cell (CSCs) from human brain tumor xenografts and stable GBM cell lines. Techniques used include FACS sorting, 3-D cultures, migration/invasion test, mouse xenografts, viability/proliferation assays, lentiviral transduction, RT-PCR, Western blotting and fluorescence microscopy.

    Name

    Kenji Watanabe*

    Position

    Postdoc, PhD

    E-mail & phone

    watanabe@cancer.dk

    Phone no.:
    +45 35 25 73 34

    Nationality

    Japanese

    Research Interest         



    My main interest is how non-proteolytic or proteolytic polyubiquitination systems are involved in the cellular response to DNA double-strand breaks.

    Name

    Robert Strauss*

    Position

    Postdoc, PhD

    E-mail & phone

    strauss@cancer.dk

    Phone no.:
    +45 35 25 77 65

    Nationality German

    Research Interest



    Analysis of the phenotypic plasticity of ovarian cancer stem cells in context with the DNA damage signaling pathway in response to genotoxic insults. Frequently used techniques include tumor xenograft models, flow cytometry-based cell sorting, and confocal microscopy.

    Name

    Matthias Altmeyer

    Position

    Postdoc, Phd

    E-mail & phone

    altmeyer@cancer.dk

    Phone no.:
    +45 35 25 77 89

    Nationality

    German

    Research Interest



    Molecular mechanisms of cellular stress response pathways, post-translational protein modifications as regulators of protein functions and principles of chromatin biology and of the regulated interplay between DNA replication, transcription and DNA repair.

    Name

    Ronni Sølvhøj Pedersen*

    Position

    PhD-student

    E-mail & phone

    ronnii@cancer.dk

    Phone no.:
    +45 35 25 77 65

    Nationality

    Danish

    Research Interest



    Identify and functionally characterize new factors that protect chromosomal integrity against genotoxic stress and elucidate their potential aberrations in cancer.

    Name

    Thorkell Gudjonnsen*

    Position

    PhD-student

    E-mail & phone

    thorkell@cancer.dk

    Phone no.:
    +45 35 25 73 47

    Nationality

    Icelandic

    Research Interest



    Cell biology, cell signaling, disease biology, chromatin biloigy, post translational modifications, epigenetics, checkpoint signaling and DNA repair.

    Name

    Martin Kosär*

    Position

    PhD student

    E-mail & phone

    kosar@cancer.dk

    Phone no.:
    +45 35 25 77 65

    Nationality Czech

    Research Interest



    Cell culture  mannipulation, DNA vector preparation, extraction and purification of DNA, gel electrophoresis, immunoflurescence, transformation, transfection, lentiviral transductin, PCR,real-time PCR and Western blotting.

    Til top

    Name

    Christophe Clouin

    Position

    PhD-student

    E-mail & phone

    chc@cancer.dk

    Phone no.:
    +45 35 25 73 47

    Nationality

    French

    Research Interest



    Understanding the cellular response to replication stress using biochemical assys, imunofluorescence and flow cytometry. Particular interest on the role of ubiquitination events during replication arrest and recovery from replication arrest.

    Name

    Luis Ignacio Toledo

    Position

    Postdoc, Phd

    E-mail & phone

    luis@cancer.dk

    Phone no.:
    +45 35 77 89

    Nationality

    Spainish

    Research Interest



    Performimg a genome-wide screen for hitherto unknown genes that induce by, or respond, to DNA replication stress. Elucdating of how these new genes contribute to intergrity maintanance. Investigating of how these mechanisms subverted in oncogenic transformation and cancer progression.
    description

    Name

    Myunghee Lee

    Position

    Laboratory Technician

    E-mail & phone

    mhl@cancer.dk

    Phone no.:
    +45 35 73 47

    Nationality

    South Korean

    Research Interest

    Protein purification stable cell and antibody screening.

    description

    Name

    Anne Arnt Kjerrulff

    Position

    Laboratory Technician

    E-mail & phone

    aak@cancer.dk

    Phone no.:
    +45 35 25 73 46

    Nationality

    Danish

    Research Interest

    Hybridoma technology, management of cell and tissue bank.

      

    Name

    Jette Christensen Sand

    Position

    Research Assistant

    E-mail & phone

    jsa@cancer.dk

    Phone no.:
    +45 35 25 73 47

    Nationality

    Danish

    Research Interest



    Antibody design and development.

    Name

    Merete Grøfte*

    Position

    Laboratory Technician

    E-mail & phone

    mergro@cancer.dk

    Phone no.:
    +45 35 25 73 47

    Nationality

    Danish

    Research Interest

    Molecular Biology and Cell  Technology.

     



    Sidst ændret: 23-06-2011




    Publications

    The chromatin- remodeling factor CHD4 coordinates signaling and repair after DNA damage

    J.Cell Biol.
    (2010, 10 1083-1093)

    Awards
     
    Dr. Jiri Bartek was awarded the prestigious 2009 Shai Shacknai Memorial Prize in Immunology and Cancer Research 0n March 15.
     
    Meetings and cources

    15th Danish Cancer Society Symposium
    Genetic Instability and Stem Cells in Cancer
    19-21 October 2009
    This event was organized by Drs. Jiri Bartek and Jiri Lukas who also served as keynote speakers.


    Sitemap